SMART Cells: Stem Cells Edited to Fight Arthritis

Using new gene-editing CRISPR technology, a team of researcher at Washington University School of Medicine rewired stem cells’ genetic circuits to autonomously produce a biologic anti-inflammatory arthritis drug when the cells encounter inflammation. The technique eventually could act as a vaccine for arthritis and other chronic conditions. Researchers successfully rewired mouse stem cells to fight inflammation. Such stem cells, known as SMART cells (Stem cells Modified for Autonomous Regenerative Therapy), could one day replace arthritic cartilage and simultaneously protect joints and other tissues from damage that occurs with chronic inflammation.

This series explores the latest science and technology news in the St. Louis area.

SMART Cells: Stem Cells Edited to Fight Arthritis

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MyStrengthBook Strengthening Their Business Through Move To Saint Louis

MyStrenthBook works with athletes to create specialized training programs. They moved to St. Louis from Canada after winning an Arch Grant.

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Meetings Go Back to the Future

Much that doesn't work about corporate meetings is being tackled by a St. Louis company that is throwing out modern tech, and using toys and cartoons instead.

Recent Segment | Innovations

Imagery-Assisted Virtual Reality for Athletic Training

SIUE athletes used imagery-assisted virtual reality to increase their confidence and performance.

Recent Segment | Innovations

How Blueberries Improve Cancer Treatment by Helping to Kill Cancer Cells

Blueberry extract combined with radiation can increase the effectiveness of cervical cancer treatment.


There are 145 more episodes of Innovations.

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Low-Cost Autonomous Car is Inspired by Insects

FlowBot is inspired by the way insects use an optical flow method to navigate and avoid obstacles in an agile manner.

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Date: April 18, 2015 Time: 10:00am