SMART Cells: Stem Cells Edited to Fight Arthritis

Using new gene-editing CRISPR technology, a team of researcher at Washington University School of Medicine rewired stem cells’ genetic circuits to autonomously produce a biologic anti-inflammatory arthritis drug when the cells encounter inflammation. The technique eventually could act as a vaccine for arthritis and other chronic conditions. Researchers successfully rewired mouse stem cells to fight inflammation. Such stem cells, known as SMART cells (Stem cells Modified for Autonomous Regenerative Therapy), could one day replace arthritic cartilage and simultaneously protect joints and other tissues from damage that occurs with chronic inflammation.

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SMART Cells: Stem Cells Edited to Fight Arthritis

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Recent Segment | Innovations

Personalized 3D Brain Maps to Guide Neurosurgeries

New personalized 3D brain maps can allow physicians to plan and perform surgeries more accurately and safely.

Recent Segment | Innovations

SirenGPS Technology Tested at Fair St. Louis: Hoping to Improve 911 Response Times

SirenGPS is a St. Louis startup that created emergency management software to help first responders find people faster when they call 911.

Recent Segment | Innovations

New Microscopic Technique Could Help Detect, Diagnose Melanomas

The fight against skin cancer just got a new weapon at the University of Missouri.

Recent Segment | Innovations

Label Insight: Providing Product Transparency Through Data Science

Label Insight offers a new level of transparency about what’s inside food and beverage products.


There are 119 more episodes of Innovations.

Recent Segment | Innovations

New Drug Delivery Method to the Brain is Tested in Locusts

Washington University engineers are exploring a new drug-delivery method to the brain using gold and locusts!

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Date: April 18, 2015 Time: 10:00am