SMART Cells: Stem Cells Edited to Fight Arthritis

Using new gene-editing CRISPR technology, a team of researcher at Washington University School of Medicine rewired stem cells’ genetic circuits to autonomously produce a biologic anti-inflammatory arthritis drug when the cells encounter inflammation. The technique eventually could act as a vaccine for arthritis and other chronic conditions. Researchers successfully rewired mouse stem cells to fight inflammation. Such stem cells, known as SMART cells (Stem cells Modified for Autonomous Regenerative Therapy), could one day replace arthritic cartilage and simultaneously protect joints and other tissues from damage that occurs with chronic inflammation.

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SMART Cells: Stem Cells Edited to Fight Arthritis

Recent Segment | Innovations

MoDOT Takes New Approach to Stopping Wrong-Way Drivers Using BlinkLink Technology

MoDOT claims success with BlinkLink, an advanced messaging and notification system using radar, cameras and sensors to stop wrong-way crashes.

Recent Segment | Innovations

Innovative SLU Lab Develops New Way to Grow Nanowires & 2D Nanostructures for Emerging Technologies

A Saint Louis University research team explains their innovative technique to produce nanoscale materials using simple processes.

Recent Segment | Innovations

Daycare Air Quality Measurement Tool Could Benefit Children's Health

Mizzou researchers develop new tool that puts air quality to the test in daycare centers.

Recent Segment | Innovations

Mizzou Multi-Disciplinary Team Develops Revolutionary Cardiovascular Stents

Mizzou partners with Nanova Biomaterials to develop better cardiovascular stents.

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Recent Segment | Innovations

St. Louis-Based SirenGPS is Successful in Texas as App Improves 911 Location Accuracy

The SirenGPS app helps first responders find people faster when they use the app's 911 panic button.

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Date: April 18, 2015 Time: 10:00am